Clinical and Translational Science, 2nd ed. by David Robertson (Editor); Gordon H. Williams (Editor), 2017Clinical and Translational Science: Principles of Human Research, Second Edition, is the most authoritative and timely resource for the broad range of investigators taking on the challenge of clinical and translational science, a field that is devoted to investigating human health and disease, interventions, and outcomes for the purposes of developing new treatment approaches, devices, and modalities to improve health. This updated second edition has been prepared with an international perspective, beginning with fundamental principles, experimental design, epidemiology, traditional and new biostatistical approaches, and investigative tools. It presents complete instruction and guidance from fundamental principles, approaches, and infrastructure, especially for human genetics and genomics, human pharmacology, research in special populations, the societal context of human research, and the future of human research. The book moves on to discuss legal, social, and ethical issues, and concludes with a discussion of future prospects, providing readers with a comprehensive view of this rapidly developing area of science. Introduces novel physiological and therapeutic strategies for engaging the fastest growing scientific field in both the private sector and academic medicine Brings insights from international leaders into the discipline of clinical and translational science Addresses drug discovery, drug repurposing and development, innovative and improved approaches to go/no-go decisions in drug development, and traditional and innovative clinical trial designs
Evidence-Based Geriatric Medicine by Jayna Holroyd-Leduc (Editor); Madhuri Reddy (Editor), 2012The latest addition to the Evidence-Based Book series, Evidence-Based Geriatric Medicine provides non-geriatrician clinicians an overview of key topics central to the care of the older patient. This guide focuses on the management of common problems in the elderly taking into account their life situations as well as treatment of specific conditions. Leading geriatricians with expertise in evidence-based medicine utilize the best available evidence and present this information in a concise, easy-to-use, question-based format. Evidence-Based Geriatric Medicine is a unique guide to the optimum management of older patients.
Evidence-Based Physical Diagnosis, Fifth ed. by Steven McGee, 2021Evidence-based insights into physical signs have evolved and progressed greatly over the past few years, further defining how physical findings identify disease, solve clinical problems, and forecast patient outcomes. Evidence-Based Physical Diagnosis, 5th Edition, is an up-to-date, authoritative resource for guidance on interpreting physical signs, enabling you to determine the most appropriate physical finding to confirm a diagnosis. Incorporating more than 200 new studies, this definitive text helps you glean the most from what you hear, see, and feel at the bedside-information that, combined with modern technologic testing, will grant clinicians the keys to outstanding patient care. Emphasizes the most important physical signs needed to determine the underlying condition or disease. Internationally renowned author Dr. Steven McGee shows readers how to pare down the multiple tests needed to confirm a diagnosis, saving both the physician and patient time and money. Features a reader-friendly outline format, including dozens of "EBM boxes" and accompanying "EBM ruler" illustrations. Contains thorough updates from cover to cover, including new evidence on the scientific value of the Romberg test (spinal stenosis); oximeter paradoxus (cardiac tamponade); platypnea (liver disease); pupil size in red eye (acute glaucoma); hum test (hearing loss); and many more. Begins each chapter with a list of Key Teaching Points, intended for readers desiring quick summaries and for teachers constructing concise bedside lessons. Features a unique evidence-based calculator online that enables you to easily determine probability using likelihood ratios. Enhanced eBook version included with purchase, which allows you to access all of the text, figures, and references from the book on a variety of devices.
Fundamentals of Evidence Based Medicine by Kameshwar Prasad 2013This is a basic book on evidence-based medicine (EBM). It starts with an introduction to the topic. It outlines the relationship between EBM and research and quality of care. Then It goes on to cover the most commonly used modules of EBM, i.e. therapy, diagnosis, prognosis and meta-analysis. Each module starts with an introduction to fundamental concepts, and description of the related research process, and then follows the critical appraisal of related type of research artcle. At the end, it covers the different systems of grading of level of evidence and strength of recommendations. The book also has three examples of critical appraisal on diagnosis, therapy, and meta-analysis.
The Massachusetts General Hospital Handbook of Behavioral Medicine: A Clinician's Guide to Evidence-based Psychosocial Interventions for Individuals with Medical Illness by Ana-Maria Vranceanu (Editor); Steven A. Safren (Editor); Joseph A. Greer (Editor), 2017This text outlines the importance of biopsychosocial factors in improving medical care, and illustrates evidence-based, state-of-the-art interventions for patients with a variety of medical conditions. Each chapter is focused on a particular health concern or illness, which is described both in terms of prevalence and frequent psychological and psychiatric comorbidities that may present to clinicians working with these populations. Consistent with evidence-based care, information on the efficacy of the treatments being described is presented to support their continued use. To accommodate the needs of clinicians, we describe population specific approaches to treatment, including goal settings, modules and skills as well as strategies to assess and monitor progress. To facilitate learning, each chapter contains one or more case examples that explicate the skills described to convey change within a behavioral medicine protocol. Each chapter also includes resources in the form of books and websites to gain additional knowledge and detail as needed. Authors are experts in the field of each chapter, ensuring that information presented is recent and of high quality.
Painless Evidence-Based Medicine by Antonio L. Dans (Editor); Leonila F. Dans (Editor); Maria Asuncion A. Silvestre (Editor), 2017This updated edition of Painless Evidence-Based Medicine presents basic concepts and application of research statistics in simple and practical manner creating an introductory approach to the complex and technical subject of evidence-based medicine from experienced teachers. A simplified introductory approach to the complex and technical subject of evidence-based medicine from experienced teachers Approaches learning from the vantage point of clinical questions on therapy, diagnosis, prognosis or harm rather than the framework of study designs Provides tables and boxed case studies throughout highlighting key topics, or difficult issues, in an easy to read manner Emphasizes applicability of EBM, encouraging readers to dissect the evidence and how results can be applied to individual patients with different circumstances, varying values and preferences New to the Second Edition are chapters on health screening, clinical practice guidelines, and major updates incorporating recommended trial criteria
Searching Skills Toolkit: Finding the Evidence, second ed. by Caroline De Brún; Nicola Pearce-Smith, 2014Searching Skills Toolkit is an expert guide to help you find the clinical evidence you need more easily and effectively. Clearly presented with useful tips and advice, flow charts, diagrams and real-life clinical scenarios, it shows the best methods for finding quality evidence. From deciding where to start, to building a search strategy, refining results and critical appraisal, it is a step-by-step guide to the process of finding healthcare evidence, and is designed for use by all health and social care professionals. This second edition has been expanded with new chapters on searching for sources to support evidence-based management decision making and how to better enable your patients to make informed choices. It has also been fully updated to include new web sources, open source reference management software, and new training resources and exercises. Searching Skills Toolkit is an ideal reference for doctors, nurses, allied health professionals, managers and decision makers, researchers and students.
Symptom to Diagnosis: An Evidence-Based Guide by Scott D. C. Stern; Adam S. Cifu; Diane Altkorn, 2020An engaging case-based approach to learning the diagnostic process in internal medicine. Symptom to Diagnosis, Fourth Edition teaches an evidence-based, step-by-step process for evaluating, diagnosing, and treating patients based on their clinical complaints. By applying this process clinicians will be able to recognize specific diseases and prescribe the most effective therapy. Each chapter is built around a common patient complaint that illustrates essential concepts and provides insight into the process by which the differential diagnosis is identified. As the case progresses, clinical reasoning is explained in detail. The differential diagnosis for that particular case is summarized in tables that highlight the clinical clues and important tests for the leading diagnostic hypothesis and alternative diagnostic hypotheses. As the chapter progresses, the pertinent diseases are reviewed. Just as in real life, the case unfolds in a stepwise fashion as tests are performed and diagnoses are confirmed or refuted. Completely updated to reflect the latest research in clinical medicine, this fourth edition is enhanced by algorithms, summary tables, questions that direct evaluation, and an examination of recently developed diagnostic tools and guidelines. Clinical pearls are featured in every chapter. Coverage for each disease includes: Textbook Presentation, Disease Highlights, Evidence-Based Diagnosis, and Treatment.
Users' Guides to the Medical Literature: a Manual for Evidence-Based Clinical Practice, 3E by Gordon Guyatt, 2015Publisher's Note: Products purchased from Third Party sellers are not guaranteed by the publisher for quality, authenticity, or access to any online entitlements included with the product. The leading guide to the principles and clinical applications of evidence-based medicine--updated with new examples and new chapters A Doody's Core Title for 2019! Revised and updated to reflect the latest in medical research and evidence-based resources Practical focus and organization to guide clinicians through the fundamentals of using the medical literature to the more advanced strategies and skills for use in patient care, using the key questions to assess any new research: What are the results? How serious is the risk of bias? How do I apply the results to patient care? Updated real-world examples drawn from the medical literature New chapters that reflect the changing complexity of medical research and literature, including genetic association studies, systematic reviews and meta-analyses, network meta-analysis, noninferiority trials, quality improvement, and evidence-based medicine and the theory of knowledge New emphasis on understanding the role of patient preferences and preappraised resources that provide updated evidence and evidence-based recommendations for practice
Databases | Research Tools
Access MedicineThis link opens in a new windowFull-text books, procedures, videos, and images in the basic sciences and medicine.
This link opens in a new window
APA PsycINFO via OvidThis link opens in a new windowContains citations and abstracts to articles in journals, dissertations, and book chapters in all areas of psychology. Includes indexing of all articles from PsycArticles.
This link opens in a new window
ClinicalKeyThis link opens in a new windowIncludes clinical overviews, full-text books and journals, drug information, procedure videos, clinical calculators, patient education handouts, practice guidelines, clinical trials, and MEDLINE® citations and abstracts. Physicians can earn and claim CME.
This link opens in a new window
Cochrane LibraryThis link opens in a new windowThe Cochrane Library is a collection of databases that contain different types of high-quality, independent evidence to inform healthcare decision-making. The Cochrane Library includes the Cochrane Database of Systematic Reviews (CDSR), the Cochrane Central Register of Controlled Trials (CENTRAL), and Cochrane Clinical Answers, and a federated search feature that incorporates results from external databases.
This link opens in a new window
EMBASEThis link opens in a new windowResearch database especially useful for systematic reviews. Search in addition to PubMed or MEDLINE.
This link opens in a new window
Lippincott AdvisorThis link opens in a new windowEvidence-based online references at the point of care. Browse by topic or category, scroll through alphabetical lists of documents, or perform a search to identify a particular document. Includes patient education handouts under Patient Teaching.
Lippincott ProceduresThis link opens in a new windowAccess nursing procedures and skills. Scroll through an alphabetical list, browse by nursing category or subcategory, or perform a search to identify a particular procedure. Each entry provides complete instructions, preparation guidelines, implementation steps, special considerations, documentation, and references. Includes video clips.
Natural MedicinesThis link opens in a new windowDatabase of evidence-based info on complementary and alternative therapies, especially drug interactions with foods, herbs, and supplements.
This link opens in a new window
PubMed @ Cleveland Clinic (On & Off Campus)This link opens in a new windowCustomized link to give full text access to Cleveland Clinic employees. PubMed provides access to bibliographic information which includes MEDLINE as well as additional life science journals. Single Citation Matcher can locate specific articles quickly. The Journal Database can help with journal abbreviations.
This link opens in a new window
PubMed Clinical QueriesThis link opens in a new windowSearch PubMed using specialized filters for clinical studies or COVID-19.
ScopusThis link opens in a new windowScopus indexes 14,000 journal titles in the scientific, technical, medical and social science literature from the mid-1960's on. Includes selected web sources and 12.7 million patents.
This link opens in a new window
Trip Database (No Advanced Search. Use default or PICO)This link opens in a new windowTrip is a clinical search engine designed to allow users to quickly and easily find and use high-quality research evidence to support their practice and/or care. In addition to manuscripts, reports, and practice guidelines, Trip includes other content types like images, videos, patient information leaflets, educational courses and news.
UpToDateThis link opens in a new windowA current clinical reference providing answers on disease management and therapy. How to search UpToDate
About the EBM Process
JAMAEvidenceThis link opens in a new windowJAMAevidence helps decision makers identify the best available evidence by providing guides to the systematic consideration of the validity, importance, and applicability of claims about the assessment of health problems and the outcomes of health care. This site includes textbooks, a glossary, calculators, and other EBM tools.
Centre for Evidence Based Medicine (CEBM) - University of OxfordCEBM aims to develop, teach and promote evidence-based health care through conferences, workshops and EBM tools so that all health care professionals can maintain the highest standards of medicine.
Created by Matt Weaver, Systems Librarian weaverm2@ccf.org at the Cleveland Clinic Floyd D. Loop Alumni Library, to provide data-driven analysis of journals when seeking publication.
BestBETsBETs were developed in the Emergency Department of Manchester Royal Infirmary, UK, to provide rapid evidence-based answers to real-life clinical questions, using a systematic approach to reviewing the literature. Although BETs initially had an emergency medicine focus, there are a significant number of BETs covering cardiothoracics, nursing, primary care and paediatrics.
ClinicalTrials.govThis link opens in a new windowClinicalTrials.gov is a registry and results database of publicly and privately supported clinical studies of human participants conducted around the world.
This link opens in a new window
CURRENT Practice Guidelines in Primary Care 2024 by Jacob A. David, 2024The authoritative guidelines primary care clinicians need to diagnose and treat the most common outpatient conditions--compiled, distilled, and updated for easy referencing Striking the perfect balance between brevity and clinical necessity, this acclaimed annual resource presents all the latest evidence-based guidelines clinicians need to treat the most common outpatient conditions. The most thorough print compendium of guidelines for primary care practice, the book features content drawn from government agencies, expert panels, medical specialty organizations, and other professional and scientific authorities. CURRENT Practice Guidelines in Primary Care 2024 converts lengthy and cumbersome text into a practical, relevant collection of available options for busy clinicians. This go-to guide converts the tremendous amount of information on the web into a practical, relevant collection of usable data for busy clinicians. Each topic is carefully selected for relevance to the office practice of ambulatory medicine and the text is presented in a convenient, easy-to-navigate outline and tabular format. *Content is drawn from a wide array of recommendations from government agencies, expert panels, medical specialty organizations, and other professional and scientific authorities * NEW: Updates reflecting the review of more than 150 guidelines *NEW: Updates to guidelines for screening/prevention of ASCVD; anxiety disorders in children, pediatric obesity, chronic pain, neonatal hyperbilirubinemia; and osteoarthritis *NEW: Numerous topics have been added, including screening and prevention of eating disorders, COVID vaccination in pregnancy, prevention of pelvic floor dysfunction, management of chest pain, left ventricular thrombus, delirium *Guideline Discordance tables highlight when major guidelines do not mirror each other * Topics are carefully selected for relevance to the office practice of ambulatory medicine, and the text is enhanced by a convenient outline and tabular format * Screening and prevention of conditions have been combined to enhance clinician use