About 2019 Novel Coronavirus (2019-nCoV)2019 Novel Coronavirus (2019-nCoV) is a virus (more specifically, a coronavirus) identified as the cause of an outbreak of respiratory illness first detected in Wuhan, China. Early on, many of the patients in the outbreak in Wuhan, China reportedly had some link to a large seafood and animal market, suggesting animal-to-person spread. However, a growing number of patients reportedly have not had exposure to animal markets, indicating person-to-person spread is occurring. At this time, it’s unclear how easily or sustainably this virus is spreading between people. The latest situation summary updates are available on CDC’s web page 2019 Novel Coronavirus, Wuhan, China.
Information for Healthcare ProfessionalsThis page includes interim guidance for healthcare professionals on human infections with 2019 novel coronavirus (2019-nCoV).
Information for LaboratoriesThis page includes interim guidance for laboratory professionals working with specimens from patients under investigation (PUI) for human infections with 2019 novel coronavirus (2019-nCoV).
OFFICIAL CDC HEALTH UPDATEThe Centers for Disease Control and Prevention (CDC) continues to closely monitor an outbreak of a 2019 novel coronavirus (2019-nCoV) in Wuhan City, Hubei Province, China that began in December 2019. CDC has established an Incident Management System to coordinate a domestic and international public health response.
Communicable Disease Threats Report, 19-25 January 2020, week 4The ECDC Communicable Disease Threats Report (CDTR) is a weekly bulletin for epidemiologists and health professionals on active public health threats. This issue covers the period 19-25 January 2020 and includes updates on Ebola virus disease, cluster of pneumonia cases associated with novel coronavirus, cholera, seasonal influenza and polio.
Novel coronavirus in ChinaChinese authorities have identified a cluster of novel coronavirus 2019-nCoV infections in Wuhan City, China. Cases have now been detected in several countries in Asia, but also in Australia, Europe and North America. All cases outside China had a recent travel history to China prior to the disease onset, except in Vietnam. The first cases in the EU/EEA were confirmed in France. Further global spread is likely.
More on situation update, epidemiological curve and global distribution
Q & A on the novel coronavirusCoronaviruses are a family of viruses causing infection in humans and a variety of animals including birds and mammals such as camels, cats and bats. Coronaviruses are zoonotic, which means they can transmit between animals and humans.
Situation update 29 January 11:00 CETSince 31 December 2019 and as of 29 January 2020, 6 074 laboratory-confirmed cases of novel coronavirus (2019-nCoV) infection, including 16 healthcare workers and 132 deaths have been reported.
2019 Novel Coronavirus Toolkit, Updated Daily (CCF intranet)About the 2019 Novel Coronavirus (2019-nCoV)
The Centers for Disease Control and Prevention (CDC) is closely monitoring an outbreak of
pneumonia in Wuhan City, Hubei Province, China. This is an evolving situation, however,
Chinese authorities have confirmed at least 300 cases. Most patients in the Wuhan City
outbreak have been epidemiologically linked to a large seafood and animal market, suggesting
a possible zoonotic origin to the outbreak. However, a growing number of patients reportedly
have not had exposure to animal markets, suggesting limited person-to-person spread is
occurring, though it’s unclear how easily or sustainably this virus is spreading between people.
A U.S. resident, who resides in the state of Washington and traveled to the Wuhan region of
China, has a confirmed infection with this virus. Travel related cases have also been reported in
Thailand, Japan, South Korea and Taiwan. A novel coronavirus (2019-nCoV) has been identified
as the cause of the outbreak. This novel coronavirus has the potential to cause severe disease
and death. Preliminary information suggests this is especially true among the elderly and those
people with underlying health problems or compromised immune systems. Many
characteristics of this novel coronavirus and how it may affect people are still unclear.
The Continuing 2019-nCoV Epidemic Threat of Novel Coronaviruses to Global Health - The Latest 2019 Novel Coronavirus Outbreak in Wuhan, ChinaThe city of Wuhan in China is the focus of global attention due to an outbreak of a febrile respiratory illness due to a coronavirus 2019-nCoV. In December 2019, there was an outbreak of pneumonia of unknown cause in Wuhan, Hubei province in China, with an epidemiological link to the Huanan Seafood Wholesale Market where there was also sale of live animals. Notification of the WHO on 31 Dec 2019 by the Chinese Health Authorities has prompted health authorities in Hong Kong, Macau, and Taiwan to step up border surveillance, and generated concern and fears that it could mark the emergence of a novel and serious threat to public health (WHO, 2020a, Parr, 2020).
Emerging Understandings of 2019-nCoVToday, we publish the first clinical data from individuals confirmed to be infected with 2019-nCoV from Wuhan, China. Chaolin Huang and colleagues provide comprehensive findings for the first 41 laboratory-confirmed cases. 27 of these 41 cases had direct exposure to the Wuhan seafood market that is thought to be the initial site of infection from an animal source. All had viral pneumonia. The severity of illness is concerning: almost a third of patients developed acute respiratory distress syndrome requiring intensive care; six patients died; five had acute cardiac injury; and four required ventilation.
Medical Journals and the 2019-nCoV OutbreakThe current outbreak of coronavirus infection is a threat to the health of the public and a breaking news story that changes hour by hour. We can eventually take a long view of how to manage and prevent epidemics, but today practitioners and public health authorities need actionable information as soon as possible.
A Novel Coronavirus From Patients With Pneumonia in China, 2019In December 2019, a cluster of patients with pneumonia of unknown cause was linked to a seafood wholesale market in Wuhan, China. A previously unknown betacoronavirus was discovered through the use of unbiased sequencing in samples from patients with pneumonia. Human airway epithelial cells were used to isolate a novel coronavirus, named 2019-nCoV, which formed a clade within the subgenus sarbecovirus, Orthocoronavirinae subfamily. Different from both MERS-CoV and SARS-CoV, 2019-nCoV is the seventh member of the family of coronaviruses that infect humans. Enhanced surveillance and further investigation are ongoing. (Funded by the National Key Research and Development Program of China and the National Major Project for Control and Prevention of Infectious Disease in China.)
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World Health Organization (WHO)
Advice for the PublicWHO’s standard recommendations for the general public to reduce exposure to and transmission of a range of illnesses are as follows, which include hand and respiratory hygiene, and safe food practices.
Disease Outbreak NewsWHO has been working with Chinese authorities and global experts from the day we were informed, to learn more about the virus, how it affects the people who are sick with it, how they can be treated, and what countries can do to respond.
Infection Prevention and Control During Health Care When Novel Coronavirus (nCoV) Infection is SuspectedThis is the first edition of guidance on infection prevention and control (IPC) strategies for use when infection with a novel coronavirus (2019-nCoV) is suspected. It has been adapted from WHO’s Infection prevention and control during health care for probable or confirmed cases of Middle East respiratory syndrome coronavirus (MERS-CoV) infection,1 based on current knowledge of the situation in China and other countries where cases were identified and experiences with severe acute respiratory syndrome (SARS)-CoV and MERS-CoV.
Novel Coronavirus (2019-nCoV)On 31 December 2019, WHO was alerted to several cases of pneumonia in Wuhan City, Hubei Province of China. The virus did not match any other known virus. This raised concern because when a virus is new, we do not know how it affects people.
Travel AdviceUpdated WHO advice for international traffic in relation to the outbreak of the novel coronavirus 2019-nCoV.
CoronavirusesA novel coronavirus, designated 2019-nCoV, was identified as the cause of a cluster of pneumonia cases in Wuhan, a city in the Hubei province of China, at the end of 2019. By late January 2020, thousands of laboratory-confirmed cases in China had been reported, and the case count has been rising daily; the majority of reports are from the Hubei province, but numerous cases have been reported in other provinces and municipalities in China, including Beijing [1,2]. Sporadic cases among travelers from Wuhan have also been reported in other countries globally (including nearby countries in Asia, as well as Australia, France, Germany, the United States [Washington state, Illinois, California, and Arizona], and Canada) [3-6]. Updated case counts in English can be found on the World Health Organization and the European Centre for Disease Prevention and Control websites.
Elsevier's Novel Coronavirus Information Center.
Novel Coronavirus Information CenterA week in late January has shown us (again) how rapidly a new disease can take root and spread. Such events are accompanied by an explosion of clinical and epidemiological information and research. The goal of this website is to open whatever resources we can to help public health authorities, researchers and clinicians contain and manage this disease. We will provide continually updated resources from Elsevier's content and experts. Our resources span scientific and medical journals and textbooks, educational products, and a variety of other resources, like travel precautions from the CDC and media posts of interest to our community.
