LitCovid tracks up-to-date scientific information about the 2019 novel Coronavirus. Most comprehensive resource on the subject, providing a central access to research articles in PubMed. Updated daily.
COVID-19 Genome Sequence DatasetA centralized sequence repository for all strains of novel corona virus (SARS-CoV-2) submitted to the National Center for Biotechnology Information (NCBI). Included are both the original sequences submitted by the principal investigator as well as SRA-processed sequences that require the SRA Toolkit for analysis.
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Clinical, Biological and Molecular Aspects of COVID-19 by Paul C. Guest (Editor), 2021The novel coronavirus 2019 (COVID-19) has caused a serious global pandemic in just eight months. Nearly every country and territory in the world has been affected by the virus. The virulence and infection rate of the virus are profound, and has required extreme social distancing measures across the globe in order to prevent overwhelming the healthcare services and hospitals. COVID-19 appears to have the greatest effects on elderly individuals and those who have co-morbid diseases, such as heart disease, asthma, and diabetes. As the peak begins to slow in many countries, the death rates remain high amidst justified fears of a second wave. A rapid worldwide mobilization has begun to identify effective treatments and develop vaccines. This new volume will increase readers' understanding of the ongoing COVID-19 pandemic through a series of chapters that address these concerns. Leading experts will discuss the effects of the virus in cases of co-morbidities, new treatment approaches, mental health aspects of the pandemic, and convey the results of survey studies. The book will be an excellent resource for researchers studying virology, metabolic diseases, respiratory disorders, and clinical scientists, physicians, drug companies, and healthcare services and workers.
Clinical Epidemiology: The Essentials, 6th ed by Grant S. Fletcher, 2021Now in its Sixth Edition, Clinical Epidemiology: The Essentials is a comprehensive, concise, and clinically oriented introduction to the subject of epidemiology. Written by expert educators, this approachable, informative text introduces students to the principles of evidence-based medicine that will help them develop and apply methods of clinical observation in order to form accurate conclusions. The updated sixth edition reflects the most current approaches to clinical epidemiology, including the latest coverage of modeling and expanded insight on applying concepts to clinical practice, with updated, clinical vignette-style end-of-chapter questions to help strengthen students' understanding and ensure a confident transition to clinical settings. Updated content throughout reflects the latest practices in clinical epidemiology. Increased emphasis on clinical judgment helps students confidently evaluate the effectiveness of guidelines and integrate them into practice. Updated vignette-style end-of-chapter questions place concepts in a clinical context and reinforce students' understanding. Key Word Lists at the start of each chapter familiarize students with critical terminology for clinical competence. Example boxes clarify the clinical implications of important concepts with relevant real-world patient care scenarios. Appendix of Additional Readings highlights trusted resources for further review.
Clinical Synopsis of COVID 19 by Hemanshu Prabhakar (Editor); Indu Kapoor (Editor); Charu Mahajan (Editor), 2020Corona virus disease or COVID-19 or SARS-CoV-2 infection is the latest pandemic that has affected humans globally. The disease has manifested itself in several forms and is now the focus of research worldwide. This book covers all the clinical aspects of the novel corona virus disease, COVID-19, which is one of the most contagious diseases ever known. It includes topics related to basic sciences, such as the virology and pathophysiology of the SARS-CoV-2 disease. It includes chapters related to symptomatology of the disease and making diagnosis, preparation of the health care workers to deal with this global pandemic. The book includes chapters on anesthetic and intensive care management of COVID-19 disease victims as these topics are of vast importance. Additionally, it includes a chapter giving insight in to the ethical aspects of the issues raised regarding disposal of bodies of the victims, as this pandemic has taken many lives across the world. It includes a chapter on special considerations to patient population such as geriatrics, pediatrics and pregnant women. The book serves as a useful resource for practitioners and clinicians in any field of medicine. It is also relevant for residents, trainees, fellows pursuing their courses in emergency medicine, anesthesia and critical care as well as postgraduates and even undergraduates. The book will serve as a ready-reckoner and useful guide for physicians from varied specialties during their clinical practice.
Covid-19 Airway Management and Ventilation Strategy for Critically Ill Older Patients by Nicola Vargas (Editor); Antonio M. Esquinas (Editor), 2020This book describes the issues and challenges that clinicians encountered in the management of older critically ill patients during the Covid-19 pandemic, and offers practical information on how to manage them. Older adults are more susceptible to complications such as acute respiratory distress syndrome (ARDS) as a result of viral pneumonia. In addition, they often have multiple comorbidities and are commonly frail, which means their various organs and systems, such as the respiratory system, have reduced functional reserves. As such, older adults are less able to react to acute stressors. During the current Covid-19 pandemic, older adult patients' mortality is increased. Further, the infection and death rates of elderly people in nursing homes and health care institutions are high. Management of older adults with Covid is complicated. The reduced availability of beds may limit their access to ICU. Moreover, the prognosis may be poor, and airway management and ventilation strategies have to take into account various clinical and physiological characteristics specific to older patients. This book is addressed to all allied professionals involved in the management of older critically ill patients and presents information collected and practical lessons learned from the clinical daily management of this population during the pandemic.
Fields Virology: Emerging Viruses (Vol. 1) by Howley & Knipe, (editors), 2021Now in four convenient volumes, Fields Virology remains the most authoritative reference in this fast-changing field, providing definitive coverage of virology, including virus biology as well as replication and medical aspects of specific virus families. This volume of Fields Virology: Emerging Viruses, Seventh Edition covers recent changes in emerging viruses, providing new or extensively revised chapters that reflect these advances in this dynamic field. Bundled with the eBook, which will be updated regularly as new information about each virus is available, including coronavirus and COVID-19, this text serves as the authoritative, up-to-date reference book for virologists, infectious disease specialists, microbiologists, and physicians, as well as medical students pursuing a career in infectious diseases. Covers both basic science and medical features of each virus, emphasizing viruses of medical importance and interest, while also including other viruses in specific cases where more is known about their mechanisms of replication or pathogenesis. Covers virus evolution, as well as Coronoviridae, Picornaviridae, Enteroviruses, Caliciviridae, Hepatitis C Virus, Filoviridae, Henipaviruses, Orthomyxoviruses, Bunyavirales, Arenaviridae, and much more. Features over 500 full-color illustrations, including key figures for use as lecture slides. Provides quick, flexible access to current information both in print and in an improved eBook format, searchable across all volumes. Discusses virus structure, virus entry, replication, and assembly, virus-host cell interactions, host immune responses and vaccines, antiviral therapeutics, virus evolution and immunization. New and forthcoming Fields Virology volumes, available in print and eBook format: DNA Viruses, RNA Viruses, Fundamental Viruses
Fields Virology: Fundamentals by Peter M. Howley; David M. Knipe; Lynn W. Enquist, 2023Now in four convenient volumes, Field's Virology remains the most authoritative reference in this fast-changing field, providing definitive coverage of virology, including virus biology as well as replication and medical aspects of specific virus families. This volume of Field's Virology: Fundamentals, Seventh Edition, edited by Drs. Peter Howley and David M. Knipe, along with volume associate editors Drs. Lynn Enquist, Jeffrey I. Cohen, Eric O. Freed, Blossom A. Damania, and Sean P. J. Whelan, focuses on the basic principles of virology and reflects recent advances in this dynamic field. Bundled with the eBook, which will be updated regularly as new information about each virus is available, this text serves as the authoritative, up-to-date reference book for virologists, infectious disease specialists, microbiologists, and physicians, as well as undergraduate and graduate students interested in virology. Includes chapters on virus structures, essential viral functions, immune responses to viral infections, viral epidemiology, viral diagnostics, and viral therapies Up to date discussions of antiviral therapies and vaccine strategies Features more than 300 full-color illustrations, including key figures for use as lecture slides Provides quick, flexible access to current information both in print and in an improved eBook format Discusses virus structure, virus entry, replication, and assembly, virus-host cell interactions, host immune responses and vaccines, antiviral therapeutics, viral persistence and latency for HIV, and mechanisms of viral oncogenesis for HPV, KSHV and the hepatotropic viruses Newly revised Field's Virology volumes, available in print and eBook format: * Emerging Viruses * DNA Viruses * RNA Viruses * Fundamental Virology Enrich Your eBook Reading Experience Read directly on your preferred device(s), such as computer, tablet, or smartphone. Easily convert to audiobook, powering your content with natural language text-to-speech.
Novel Coronavirus 2019 by Amit Kumar; Ajit Kumar Saxena; Gwo Giun Chris Lee; Amita Kashyap; G. Jyothsna, 2020This book highlights the genomic findings, observations, and analysis of DNA/RNA sequences and protein structure of the dreadful virus of this decade- COVID-19. The Corona group of viruses though known species, the strain that caused the Pandemic of 2019 is a completely new strain, belonging to the same corona family with a novel genetic make-up. This makes it a new pathogen which is causing the current outbreak leaving the global scientific community clueless of any therapeutic breakthrough. NCOV enjoys life threatening pathogenicity with mysterious genetic annotations. This book details and offers insights into its viral genetic arrangement, Virulence factors, probable mutations leading to the evolution of this new strain and more. It contains chapters on Virus evolutionary status and Genetic makeup leading to its pathogenicity which can be a new insight in understanding the nature of this clever microorganism and can pave way to the development of new drugs and Vaccines or a novel diagnostic approach for the early prognosis of the disease. A dedicated chapter on annotation of NCOV-19 virulence genes, translation of the genes to protein product, annotation of the antigenic sites on these proteins is also included. In all, this brief is a complete genomic annotation insight of NCOV-19 using AI, Data analytics and Bioinformatics analysis. In the current situation, this book is an extensive preliminary resource for Medical practitioners, Researchers, Academicians, Scientists, Biochemists, Bioinformaticians and other professionals interested in understanding the genetics of Novel Coronavirus 19, the best possible drug targets, ideal vaccine candidates and novel prognostic and diagnostic biomarkers.
Textbook of SARS-CoV-2 and COVID-19 by Subramani Mani; Jorn-Hendrik Weitkamp, 2024Written by physicians and scientists with expertise in this evolving area, Textbook of SARS-CoV-2 and COVID-19 provides a coherent, readable, and clinically relevant review of the biology, epidemiology, pathophysiology, immunology, clinical features, current treatment, and prevention strategies for the SARS-CoV-2 virus. Using both a systemic and topic-based approach, it summarizes and clarifies the extensive literature published on SARS-CoV-2 and COVID-19, includes a comprehensive bibliography, and provides answers to clinical questions at the point of care from multiple specialty perspectives. Includes dedicated chapters for pulmonary, cardiac, neurological, and oral manifestations of COVID-19. Covers therapeutics and novel therapeutic targets of SARS-CoV-2 and COVID-19. Addresses the diagnostic and management challenges of COVID-19 in the emergency department. Discusses COVID-19 in special populations, including the effect of SARS-CoV-2 infection in pregnant mothers and to the fetus and newborn. Provides a systematic overview and comparison of vaccines that are approved and in development. Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.
Clinical Epidemiology: The Essentials, 6th ed by Grant S. Fletcher, 2021Now in its Sixth Edition, Clinical Epidemiology: The Essentials is a comprehensive, concise, and clinically oriented introduction to the subject of epidemiology. Written by expert educators, this approachable, informative text introduces students to the principles of evidence-based medicine that will help them develop and apply methods of clinical observation in order to form accurate conclusions. The updated sixth edition reflects the most current approaches to clinical epidemiology, including the latest coverage of modeling and expanded insight on applying concepts to clinical practice, with updated, clinical vignette-style end-of-chapter questions to help strengthen students' understanding and ensure a confident transition to clinical settings. Updated content throughout reflects the latest practices in clinical epidemiology. Increased emphasis on clinical judgment helps students confidently evaluate the effectiveness of guidelines and integrate them into practice. Updated vignette-style end-of-chapter questions place concepts in a clinical context and reinforce students' understanding. Key Word Lists at the start of each chapter familiarize students with critical terminology for clinical competence. Example boxes clarify the clinical implications of important concepts with relevant real-world patient care scenarios. Appendix of Additional Readings highlights trusted resources for further review.
Fields Virology: Emerging Viruses (Vol. 1) by Howley & Knipe, (eds), 2021Now in four convenient volumes, Fields Virology remains the most authoritative reference in this fast-changing field, providing definitive coverage of virology, including virus biology as well as replication and medical aspects of specific virus families. This volume of Fields Virology: Emerging Viruses, Seventh Edition covers recent changes in emerging viruses, providing new or extensively revised chapters that reflect these advances in this dynamic field. Bundled with the eBook, which will be updated regularly as new information about each virus is available, including coronavirus and COVID-19, this text serves as the authoritative, up-to-date reference book for virologists, infectious disease specialists, microbiologists, and physicians, as well as medical students pursuing a career in infectious diseases. Covers both basic science and medical features of each virus, emphasizing viruses of medical importance and interest, while also including other viruses in specific cases where more is known about their mechanisms of replication or pathogenesis. Covers virus evolution, as well as Coronoviridae, Picornaviridae, Enteroviruses, Caliciviridae, Hepatitis C Virus, Filoviridae, Henipaviruses, Orthomyxoviruses, Bunyavirales, Arenaviridae, and much more. Features over 500 full-color illustrations, including key figures for use as lecture slides. Provides quick, flexible access to current information both in print and in an improved eBook format, searchable across all volumes. Discusses virus structure, virus entry, replication, and assembly, virus-host cell interactions, host immune responses and vaccines, antiviral therapeutics, virus evolution and immunization. New and forthcoming Fields Virology volumes, available in print and eBook format: DNA Viruses, RNA Viruses, Fundamental Viruses
Textbook of SARS-CoV-2 and COVID-19 by Subramani Mani; Jorn-Hendrik Weitkamp, 2024Written by physicians and scientists with expertise in this evolving area, Textbook of SARS-CoV-2 and COVID-19 provides a coherent, readable, and clinically relevant review of the biology, epidemiology, pathophysiology, immunology, clinical features, current treatment, and prevention strategies for the SARS-CoV-2 virus. Using both a systemic and topic-based approach, it summarizes and clarifies the extensive literature published on SARS-CoV-2 and COVID-19, includes a comprehensive bibliography, and provides answers to clinical questions at the point of care from multiple specialty perspectives. Includes dedicated chapters for pulmonary, cardiac, neurological, and oral manifestations of COVID-19. Covers therapeutics and novel therapeutic targets of SARS-CoV-2 and COVID-19. Addresses the diagnostic and management challenges of COVID-19 in the emergency department. Discusses COVID-19 in special populations, including the effect of SARS-CoV-2 infection in pregnant mothers and to the fetus and newborn. Provides a systematic overview and comparison of vaccines that are approved and in development. Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.